Physiology and Pharmacology of Post Tissue Injury ProcessingProduct #: PAIN2016-1962
- Characterize changes in the response of the primary afferent exposed to inflammatory conditions
Review system properties that lead after local injury to: i) an enhanced response to otherwise non aversive stimuli and ii) to changes in receptive field size (e.g. secondary hyperalgesia)
Review key aspects of the complex pharmacology which regulate the input/output function of dorsal horn neurons in normal and post tissue injury pain states
Discuss changes in neural processing that lead from an acute (transient) pain state to a persistent pain state.